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History & Cause of MS

In 1860, French neurologist, Jean-Martin Charcot, first discovered MS in a patient that he was examining, Dr. Moxon, a neurologist in England recognized MS in 1873, and in the United States Dr. Seguin recognized the illness in 1878. Many aspects of the illness were observed by the end of the century. One of which was the fact that the disease was more common in women than in men.

In the 1900's, research began to grow complex. In 1919, for the first time, abnormalities in spinal fluid were noted. Dr. Edgar Adrian established techniques necessary to study nerve activity and began experimentation in this regard. During this period, new methods and understandings emerged such as the actual composition of myelin.

In 1947, Dr. Kabat of Columbia University identified abnormal immunologic proteins in the spinal fluid and noted a pattern called oligoclonal bands. In the 1950's, neurologists began to more easily identify MS, its symptoms, and signs. It's important to note since those early days that significant strides have been made with research, treatment, and how MS is viewed.

MS: The Cause

The cause of MS still remains a mystery, although various "clues" have been investigated such as climate, age, genetics, immunology, and viruses. To date, researchers have not found a causal factor. Some researchers believe that there are multiple issues at hand concerning the cause of the illness, while others believe that is is one identifiable factor.

MS: Which Organs Effect Specific Functions

The brain consists of two main areas: A pair of hemispheres on top and the brainstem on the bottom. The hemispheres are connected together by nerve fibers called the Corpus Callosum. Each hemisphere is divided into four lobes.

The Frontal Lobes are used for planning, judgment and movement, the Temporal Lobes are used for memory, the Parietal Lobes are used for senses, and the Occipital Lobes are used for vision. Deep within the hemispheres lies the Limbic System, which is responsible for our emotions. The brainstem carries impulses down to the nerves into the spinal cord. Just behind the brainstem is the Cerebellum, which controls our sense of balance and coordination. MS effects the brain and central nervous system, which includes the spinal cord area.


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